Title : CYP17 inhibitors--abiraterone, C17,20-lyase inhibitors and multi-targeting agents.

Pub. Date : 2014 Jan

PMID : 24276076






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 As the first in class steroid 17alpha-hydroxylase/C17,20-lyase (CYP17) inhibitor, abiraterone acetate (of which the active metabolite is abiraterone) has been shown to improve overall survival in patients with castration-resistant prostate cancer (CRPC)--in those who are chemotherapy-naive and those previously treated with docetaxel. Abiraterone Acetate cytokine like 1 Homo sapiens