Title : Rupatadine inhibits inflammatory mediator release from human laboratory of allergic diseases 2 cultured mast cells stimulated by platelet-activating factor.

Pub. Date : 2013 Dec

PMID : 24267366






1 Functional Relationships(s)
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1 RESULTS: PAF stimulated a statistically significant release of histamine, interleukin-8, and tumor necrosis factor (0.001-0.1 mumol/L) that was comparable to that stimulated by substance P. Pretreatment with RUP (25 mumol/L) for 10 minutes inhibited this effect. Histamine PCNA clamp associated factor Homo sapiens