Title : Engineering an effective immune adjuvant by designed control of shape and crystallinity of aluminum oxyhydroxide nanoparticles.

Pub. Date : 2013 Dec 23

PMID : 24261790






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Other than being comprised of micrometer-sized aggregates that include nanoscale particulates, Alum lacks specific physicochemical properties to explain activation of the innate immune system, including the mechanism by which aluminum-based adjuvants engage the NLRP3 inflammasome and IL-1beta production. Aluminum NLR family pyrin domain containing 3 Homo sapiens