Title : Two surfaces of cytochrome b5 with major and minor contributions to CYP3A4-catalyzed steroid and nifedipine oxygenation chemistries.

Pub. Date : 2014 Jan 1

PMID : 24256945






1 Functional Relationships(s)
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1 Here, we show that b5 mutations E48G, E49G, D58G, and D65G have reduced capacity to stimulate CYP3A4-catalyzed progesterone and testosterone 6beta-hydroxylation or nifedipine oxidation. Progesterone cytochrome P450 family 3 subfamily A member 4 Homo sapiens