Title : IgE-mediated activation of human heart in vitro.

Pub. Date : 1986 Apr

PMID : 2425583






4 Functional Relationships(s)
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1 Rabbit anti-human IgE (1-10 micrograms/ml) dose-dependently induced the release of histamine (5 to 15% of the total histamine content) and of PGD2 (5 to 100 ng/g of wet tissue). Histamine immunoglobulin heavy constant epsilon Homo sapiens
2 Rabbit anti-human IgE (1-10 micrograms/ml) dose-dependently induced the release of histamine (5 to 15% of the total histamine content) and of PGD2 (5 to 100 ng/g of wet tissue). Histamine immunoglobulin heavy constant epsilon Homo sapiens
3 A significant linear correlation (rs = 0.90; p less than 0.001) was found between de novo synthesis of PGD2 and the secretion of histamine induced by anti-IgE challenge of human heart. Histamine immunoglobulin heavy constant epsilon Homo sapiens
4 Additionally, anti-IgE challenge of human heart in vitro induces the release of histamine and PGD2. Histamine immunoglobulin heavy constant epsilon Homo sapiens