Title : ATM-depletion in breast cancer cells confers sensitivity to PARP inhibition.

Pub. Date : 2013 Nov 19

PMID : 24252502






1 Functional Relationships(s)
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1 RESULTS: When ATM-depleted cells and their relative controls were treated with olaparib (a competitive PARP-1/2 inhibitor) and iniparib (a molecule originally described as a covalent PARP-1 inhibitor) a different response to the two compounds was observed. olaparib poly(ADP-ribose) polymerase family member 12 Homo sapiens