Title : Key proteins in the polyamine-trypanothione pathway as drug targets against Trypanosoma cruzi.

Pub. Date : 2014

PMID : 24251576






1 Functional Relationships(s)
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1 In trypanosomatids, redox homeostasis is centered on trypanothione (N(1),N(8)-bis(glutathionyl)spermidine, T(SH)2), a low molecular weight thiol that is distinctive for this taxonomic family and not present in the mammalian host. trypanothione threonine synthase like 2 Homo sapiens