Title : Bile salt inhibition of host cell damage by Clostridium difficile toxins.

Pub. Date : 2013

PMID : 24244530






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Using caspase-3 and lactate dehydrogenase assays, we have demonstrated that taurocholate reduced the extent of toxin B-induced apoptosis and cell membrane damage. Taurocholic Acid caspase 3 Homo sapiens
2 Remarkably, addition of 5 mM taurocholate reduced caspase-3 activity in cells treated with 2, 4, 6, and 12 microg/ml of toxin B by 99%, 78%, 64%, and 60%, respectively. Taurocholic Acid caspase 3 Homo sapiens