Title : Structural basis for recognition of synaptic vesicle protein 2C by botulinum neurotoxin A.

Pub. Date : 2014 Jan 2

PMID : 24240280






2 Functional Relationships(s)
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1 Two types of BoNT/A receptor have been identified, both of which are required for BoNT/A toxicity and are therefore likely to cooperate with each other: gangliosides and members of the synaptic vesicle glycoprotein 2 (SV2) family, which are putative transporter proteins that are predicted to have 12 transmembrane domains, associate with the receptor-binding domain of the toxin. bont synaptic vesicle glycoprotein 2A Homo sapiens
2 Two types of BoNT/A receptor have been identified, both of which are required for BoNT/A toxicity and are therefore likely to cooperate with each other: gangliosides and members of the synaptic vesicle glycoprotein 2 (SV2) family, which are putative transporter proteins that are predicted to have 12 transmembrane domains, associate with the receptor-binding domain of the toxin. bont synaptic vesicle glycoprotein 2A Homo sapiens