Title : Specific HLA types are associated with antiepileptic drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in Japanese subjects.

Pub. Date : 2013 Nov

PMID : 24236482






2 Functional Relationships(s)
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Protein Name
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1 HLA-A*02:07 and HLA-B*51:01, in a dominant model, were significantly associated with zonisamide- and phenobarbital-induced SJS/TEN, respectively (Pc = 0.0176 and 0.0042, respectively). Zonisamide major histocompatibility complex, class I, B Homo sapiens
2 CONCLUSION: Our data suggest that HLA-A*02:07 and HLA-B*51:01 are potential biomarkers for zonisamide- and phenobarbital-induced SJS/TEN, respectively, in Japanese individuals. Zonisamide major histocompatibility complex, class I, B Homo sapiens