Title : Simvastatin sensitizes human gastric cancer xenograft in nude mice to capecitabine by suppressing nuclear factor-kappa B-regulated gene products.

Pub. Date : 2014 Mar

PMID : 24233024






1 Functional Relationships(s)
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1 As compared to the vehicle control, simvastatin also suppressed the expression of NF-kappaB-regulated gene products such as cyclin D1, COX-2, ICAM-1, MMP-9, survivin, Bcl-xL, and XIAP in tumor tissues. Simvastatin intercellular adhesion molecule 1 Homo sapiens