Title : The crystal structure of shiga toxin type 2 with bound disaccharide guides the design of a heterobifunctional toxin inhibitor.

Pub. Date : 2014 Jan 10

PMID : 24225957






1 Functional Relationships(s)
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1 We have determined the first crystal structure of a disaccharide analog of Gb3 bound to the B5 pentamer of Stx2a holotoxin. Disaccharides alpha 1,4-galactosyltransferase (P blood group) Homo sapiens