Pub. Date : 2014 Jan
PMID : 24220725
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Extract of Bryophyllum laetivirens reverses etoposide resistance in human lung A549 cancer cells by downregulation of NF-kappaB. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | We first found that lung cancer A549 cells resistant to etoposide (A549RT-eto) exhibit upregulation of NF-kappaB and SIRT1 in comparison to A549 parental cells. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | Taken together, we suggest that upregulation of NF-kappaB determines etoposide resistance through P-gp expression in human A549 lung cancer cells. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | We herein demonstrated that B. laetivirens extract reverses etoposide resistance in human A549 lung cancer cells through downregulation of NF-kappaB. | Etoposide | nuclear factor kappa B subunit 1 | Homo sapiens |