Title : Sanguinarine inhibits invasiveness and the MMP-9 and COX-2 expression in TPA-induced breast cancer cells by inducing HO-1 expression.

Pub. Date : 2014 Jan

PMID : 24220687






3 Functional Relationships(s)
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Protein Name
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1 Sanguinarine inhibits invasiveness and the MMP-9 and COX-2 expression in TPA-induced breast cancer cells by inducing HO-1 expression. Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens
2 Thus, knockdown of endogenous HO-1 decreased TPA-induced cell invasion. Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens
3 Overall, the results of the present study demonstrate that HO-1 plays a pivotal role in the anti-invasive response of sanguinarine in TPA-stimulated breast cancer cells. Tetradecanoylphorbol Acetate heme oxygenase 1 Homo sapiens