Title : Contribution of oligomerization to the anti-HIV-1 properties of SAMHD1.

Pub. Date : 2013 Nov 12

PMID : 24219908






2 Functional Relationships(s)
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1 In agreement with these observations, the Y146S/Y154S variant of a bacterial construct expressing the HD domain of human SAMHD1 (residues 109-626) disrupted the dGTP-dependent tetramerization of SAMHD1 in vitro. deoxyguanosine triphosphate SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens
2 In agreement with these observations, the Y146S/Y154S variant of a bacterial construct expressing the HD domain of human SAMHD1 (residues 109-626) disrupted the dGTP-dependent tetramerization of SAMHD1 in vitro. deoxyguanosine triphosphate SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Homo sapiens