Pub. Date : 2013 Dec
PMID : 24219282
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Arachidonic acid stimulates cell adhesion by activating alpha2beta1 integrins in a process that depends on protein kinases, including p38 mitogen activated protein kinase. | Arachidonic Acid | mitogen-activated protein kinase 14 | Homo sapiens |
| 2 | Confocal microscopy of arachidonic acid-treated cells showed that vinculin and phospho-p38 both appeared enriched in pseudopodia and at the tips of actin filaments, and fluorescence ratio imaging indicated the increase was specific for the phospho-(active) form of p38. | Arachidonic Acid | mitogen-activated protein kinase 14 | Homo sapiens |
| 3 | Confocal microscopy of arachidonic acid-treated cells showed that vinculin and phospho-p38 both appeared enriched in pseudopodia and at the tips of actin filaments, and fluorescence ratio imaging indicated the increase was specific for the phospho-(active) form of p38. | Arachidonic Acid | mitogen-activated protein kinase 14 | Homo sapiens |
| 4 | Immunoprecipitates of phospho-p38 from extracts of arachidonic acid-treated cells contained vinculin, and GST-vinculin fusion proteins carrying the central region of vinculin bound phospho-p38, whereas fusion proteins expressing the terminal portions of vinculin did not. | Arachidonic Acid | mitogen-activated protein kinase 14 | Homo sapiens |
| 5 | Immunoprecipitates of phospho-p38 from extracts of arachidonic acid-treated cells contained vinculin, and GST-vinculin fusion proteins carrying the central region of vinculin bound phospho-p38, whereas fusion proteins expressing the terminal portions of vinculin did not. | Arachidonic Acid | mitogen-activated protein kinase 14 | Homo sapiens |