Title : [Abelson interactor 1 (Abi1) in colorectal cancer. From synaptic plasticity to tumor cell migration].

Pub. Date : 2013 Nov

PMID : 24196611






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A phosphorylated isoform of Abi1 that stains positively in these microcompartments disappears after treatment with the tyrosine kinase inhibitor STI571 (Glivec ). Imatinib Mesylate abl interactor 1 Homo sapiens
2 As phosphorylation of Abi1 could be pharmaceutically targeted with STI571, this indicates a possible therapeutic option to prevent the gain of a metastatic phenotype in colorectal cancer. Imatinib Mesylate abl interactor 1 Homo sapiens