Title : The Influence of IgE on Cultured Human Mast Cells.

Pub. Date : 2013 Nov

PMID : 24179689






3 Functional Relationships(s)
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1 It was observed how the IgE concentration affects the histamine release, FcepsilonRI density on the mast cell surface and the concentration of other mediators. Histamine immunoglobulin heavy constant epsilon Homo sapiens
2 RESULTS: A clear correlation between IgE concentration in culture medium and the release of histamine upon activation was observed. Histamine immunoglobulin heavy constant epsilon Homo sapiens
3 CONCLUSIONS: IgE in the culture medium during the last 10 days of mast cell maturation influences the release of the preformed mediator histamine after mast cell activation and the density of FcepsilonRI on the mast cell surface. Histamine immunoglobulin heavy constant epsilon Homo sapiens