Title : c-ABL tyrosine kinase modulates p53-dependent p21 induction and ensuing cell fate decision in response to DNA damage.

Pub. Date : 2014 Feb

PMID : 24177958






1 Functional Relationships(s)
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1 When these cells were simultaneously treated with a c-ABL kinase inhibitor, STI571, or a c-ABL-specific siRNA along with adriamycin, the p53-dependent p21 induction was dramatically diminished, even though p53 is substantially induced. Imatinib Mesylate tumor protein p53 Homo sapiens