Title : Small molecule sensitization to TRAIL is mediated via nuclear localization, phosphorylation and inhibition of chaperone activity of Hsp27.

Pub. Date : 2013 Oct 31

PMID : 24176848






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 LY303511-induced nuclear translocation of Hsp27 is linked to its sustained phosphorylation via activation of p38 kinase and MAPKAP kinase 2 and the inhibition of PP2A. LY 303511 MAPK activated protein kinase 2 Homo sapiens