Title : Reversal effect of bufalin on multidrug resistance in human hepatocellular carcinoma BEL-7402/5-FU cells.

Pub. Date : 2014 Jan

PMID : 24173654






1 Functional Relationships(s)
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1 Bufalin significantly arrested the cell cycle at the G0/G1 phase, induced apoptosis through an increase in the Bax/Bcl-xL ratio, inhibited drug efflux pump activity via downregulation of MRP1, and reduced the expression of TS in BEL-7402/5-FU cells. bufalin ATP binding cassette subfamily B member 1 Homo sapiens