Title : Polarization of the innate immune response by prostaglandin E2: a puzzle of receptors and signals.

Pub. Date : 2014 Jan

PMID : 24170779






1 Functional Relationships(s)
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1 The biosynthesis of eicosanoids includes as the first step the Ca(2+)- and kinase-dependent activation of the cytosolic phospholipase A2, which releases arachidonic acid from membrane phospholipids, and later events depending on the transcriptional regulation of the enzymes of the cyclooxygenase routes, where PGE2 is the most relevant product. Dinoprostone phospholipase A2 group IVA Homo sapiens