Title : L-carnitine protects against cyclosporine-induced pancreatic and renal injury in rats.

Pub. Date : 2013 Oct

PMID : 24157049






1 Functional Relationships(s)
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1 RESULTS: CsA treatment caused diabetes, renal dysfunction, tubulointerstitial inflammation (ED-1-positive cells), and fibrosis, which were accompanied by an increase in 8-OHdG production and upregulation of TGF-beta1, caspase-3, and LC3-II. Cyclosporine caspase 3 Rattus norvegicus