Title : A degradative detour for mutant TP53.

Pub. Date : 2013 Dec

PMID : 24145670






1 Functional Relationships(s)
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1 In a recent issue of Genes & Development, we demonstrated that blocking macroautophagy under nutritional stress condition leads to the degradation of mutant TP53 through activating the chaperone-mediated autophagy (CMA) pathway in nonproliferating cancer cells. Adenosine Monophosphate tumor protein p53 Homo sapiens