Title : Minnelide: a novel therapeutic that promotes apoptosis in non-small cell lung carcinoma in vivo.

Pub. Date : 2013

PMID : 24143232






1 Functional Relationships(s)
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1 Triptolide/Minnelide significantly down-regulated the expression of pro-survival and anti-apoptotic genes (HSP70, BIRC5, BIRC4, BIRC2, UACA) and up-regulated pro-apoptotic APAF-1 gene, in part, via attenuating the NF-kappaB signaling activity. 14-O-phosphonooxymethyltriptolide disodium salt heat shock protein 1B Mus musculus