Pub. Date : 1985 Mar-Apr
PMID : 2412213
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | GRP10 was catabolized by gastric muscle peptidases (specific activity 1.8 nmol min-1 mg-1 protein) by hydrolysis of the His8-Leu9 bond and catabolism was inhibited by phosphoramidon (I50 approx. | phosphoramidon | gastrin releasing peptide | Homo sapiens |
| 2 | The same bond in GRP10 was cleaved by purified endopeptidase-24.11, and hydrolysis was equally sensitive to inhibition by phosphoramidon. | phosphoramidon | gastrin releasing peptide | Homo sapiens |
| 3 | It is concluded that a membrane-bound peptidase in the stomach wall catabolizes and inactivates GRP10 and SP and that, in its specificity and sensitivity to phosphoramidon, this peptidase resembles endopeptidase-24.11. | phosphoramidon | gastrin releasing peptide | Homo sapiens |