Title : The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5.

Pub. Date : 2014 Jan

PMID : 24117196






1 Functional Relationships(s)
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1 BACKGROUND AND PURPOSE: Treatment with methadone is associated with severe cardiac arrhythmias, a side effect that seems to result from an inhibition of cardiac hERG K+ channels. Methadone ETS transcription factor ERG Homo sapiens