Title : Genotype variant associated with add-on memantine in bipolar II disorder.

Pub. Date : 2014 Feb

PMID : 24103632






2 Functional Relationships(s)
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1 To adjust within-subject dependence over repeated assessments, multiple linear regression with generalized estimating equation methods was used to analyze the effects of the BDNF Val66Met polymorphism on the clinical performance of memantine. Memantine brain derived neurotrophic factor Homo sapiens
2 We conclude that the BDNF Val66Met polymorphism influenced responses to add-on memantine by decreasing depressive symptoms in patients with BP-II. Memantine brain derived neurotrophic factor Homo sapiens