Title : Role of reactive oxygen intermediates in the interferon-mediated depression of hepatic drug metabolism and protective effect of N-acetylcysteine in mice.

Pub. Date : 1985 Aug

PMID : 2410095






1 Functional Relationships(s)
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1 The results suggest that an increased endogenous generation of free radicals, possibly due to the induction of xanthine oxidase, is implicated in the IFN-mediated depression of liver drug metabolism. Free Radicals xanthine dehydrogenase Mus musculus