Title : Novel compound 1,3-bis (3,5-dichlorophenyl) urea inhibits lung cancer progression.

Pub. Date : 2013 Dec 15

PMID : 24099794






1 Functional Relationships(s)
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1 The successful clinical management of lung cancer is limited by frequent loss-of-function mutations in p53 which cooperates with chronic oxidant-stress induced adaptations in mercapturic acid pathway (MAP) which in turn regulates critical intracellular signaling cascades that determine therapeutic refractoriness. Acetylcysteine tumor protein p53 Homo sapiens