Pub. Date : 2013 Nov
PMID : 24096875
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | p53"s choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. | Oxygen | tumor protein p53 | Homo sapiens |
| 2 | p53"s choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. | Oxygen | tumor protein p53 | Homo sapiens |
| 3 | p53"s choice of myocardial death or survival: Oxygen protects infarct myocardium by recruiting p53 on NOS3 promoter through regulation of p53-Lys(118) acetylation. | Oxygen | tumor protein p53 | Homo sapiens |
| 4 | p53 exhibited a differential DNA-binding, namely, BAX-p53RE in the infarct heart or NOS3-p53RE in the oxygenated heart, which was regulated by oxygen-induced, post-translational modification of p53. | Oxygen | tumor protein p53 | Homo sapiens |
| 5 | In the infarct heart, p53 was heavily acetylated at Lys(118) residue, which was exclusively reversed in the oxygenated heart, apparently regulated by oxygen-dependent expression of TIP60. | Oxygen | tumor protein p53 | Homo sapiens |
| 6 | Understanding this novel oxygen-p53 survival pathway will open new avenues in cardioprotection molecular therapy. | Oxygen | tumor protein p53 | Homo sapiens |