Pub. Date : 2013 Dec 1
PMID : 24090815
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Significant increase of P450 total content and hydroxyl radical levels by low, high doses of ETBE and PB treatments at weeks 1 and 2, and 8-OHdG formation at week 2, accompanied accumulation of CYP2B1/2B2, CYP3A1/3A2 and CYP2C6, and downregulation of DNA oxoguanine glycosylase 1, induction of apoptosis and cell cycle arrest in hepatocytes, respectively. | Phenobarbital | cytochrome P450, family 3, subfamily a, polypeptide 23-polypeptide 1 | Rattus norvegicus |