Title : Design, synthesis and molecular docking of novel N,N-dimethylbenzenesulfonamide derivatives as potential antiproliferative agents.

Pub. Date : 2014 Oct

PMID : 24090422






2 Functional Relationships(s)
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1 Biological screening results showed that sulfonamides 6, 9, 11, 16 and 17 with IC50 values 21.81, 25.50, 20.60, 25.83 and 31.20 muM, respectively, possessed higher antiproliferative activity compared to doxorubicin, IC50 value 32.00 muM, as position control. Sulfonamides latexin Homo sapiens
2 Biological screening results showed that sulfonamides 6, 9, 11, 16 and 17 with IC50 values 21.81, 25.50, 20.60, 25.83 and 31.20 muM, respectively, possessed higher antiproliferative activity compared to doxorubicin, IC50 value 32.00 muM, as position control. Sulfonamides latexin Homo sapiens