Title : Transforming growth factor-beta regulates production of proteoglycans by mesangial cells.

Pub. Date : 1990 Feb

PMID : 2407884






2 Functional Relationships(s)
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Protein Name
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1 In control experiments we found that mesangial cells produced two distinct proteoglycans identified as the small chondroitin/dermatan sulfate proteoglycans biglycan (PG I) and decorin (PG II) by showing that their mobility on SDS-PAGE changed upon digestion by chondroitinase ABC, and that they reacted with antibodies raised against synthetic peptides from the core protein sequence of human biglycan and decorin. Dermatan Sulfate biglycan Homo sapiens
2 In control experiments we found that mesangial cells produced two distinct proteoglycans identified as the small chondroitin/dermatan sulfate proteoglycans biglycan (PG I) and decorin (PG II) by showing that their mobility on SDS-PAGE changed upon digestion by chondroitinase ABC, and that they reacted with antibodies raised against synthetic peptides from the core protein sequence of human biglycan and decorin. Dermatan Sulfate biglycan Homo sapiens