Title : Genetic interactions within inositol-related pathways are associated with longitudinal changes in ventricle size.

Pub. Date : 2014

PMID : 24077433






1 Functional Relationships(s)
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1 Both genes belong to the inositol phosphate signaling pathway which has been previously associated with neurodegeneration in AD and we discuss the possibility that perturbation of this pathway results in a down-regulation of the Akt cell survival pathway and, thereby, decreased neuronal survival, as reflected by increased volume of the ventricles. Inositol Phosphates AKT serine/threonine kinase 1 Homo sapiens