Title : Neuroblastoma-related inflammation: May small doses of aspirin be suitable for small cancer patients?

Pub. Date : 2013 Jul 1

PMID : 24073359






1 Functional Relationships(s)
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1 The continuous administration of low-dose aspirin to TH-MYCN mice (a model of pediatric neuroblastoma) delays tumor outgrowth and decreases tumor-promoting inflammation by inhibiting regulatory cells of the innate immune system as well as immunosuppressive mediators such as transforming growth factor beta (TGFbeta) and thromboxane A2. Aspirin v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived Mus musculus