Title : Hydrogen-exchange study of the conformational stability of human carbonic-anhydrase B and its metallocomplexes.

Pub. Date : 1975 Aug 1

PMID : 240709






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 At pH 4.6 the addition of Co(II), Cd(II) or Mn(II) to the apoenzyme results in a destabilization of the native protein conformation, but in the range of pH 5.5--8.8 these metal ions, and Zn(II), slightly increase the conformational stability of the protein, in so far as they reduce the probability phi of solvent exposure of the peptide groups. Metals mitochondrially encoded cytochrome c oxidase II Homo sapiens