Title : Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA.

Pub. Date : 2013 Oct 23

PMID : 24063363






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Previous studies show that N-glycosidic bond hydrolysis follows a stepwise (S(N)1) mechanism, and that TDG activity increases with pyrimidine N1 acidity, that is, leaving group quality of the target base. pyrimidine thymine DNA glycosylase Homo sapiens