Pub. Date : 2013
PMID : 24062859
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Finally, HMGA1 binding affinity to DNA was found to be influenced by the DNA A:T segment sequence context, with higher specificity be observed in HMGA1 binding to TnAn segments, which have two local minor groove minima on either side of the TpA step, compared to An:Tn segments, which have a single minor groove minimum at the 3" end of the An run, implying AT-hook binding favors narrow minor groove structure. | Tetradecanoylphorbol Acetate | high mobility group AT-hook 1 | Homo sapiens |
| 2 | Finally, HMGA1 binding affinity to DNA was found to be influenced by the DNA A:T segment sequence context, with higher specificity be observed in HMGA1 binding to TnAn segments, which have two local minor groove minima on either side of the TpA step, compared to An:Tn segments, which have a single minor groove minimum at the 3" end of the An run, implying AT-hook binding favors narrow minor groove structure. | Tetradecanoylphorbol Acetate | high mobility group AT-hook 1 | Homo sapiens |