Title : The Role of Genetic Sex in Affect Regulation and Expression of GABA-Related Genes Across Species.

Pub. Date : 2013

PMID : 24062698






2 Functional Relationships(s)
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1 Second, using gene co-expression network analysis in control human subjects (N = 214; two frontal cortex regions) and expression quantitative trait loci mapping (N = 170 subjects), we show that expression of SST and the GABA-synthesizing enzymes glutamate decarboxylase 67 (GAD67) and GAD65 are tightly co-regulated and influenced by X-chromosome genetic polymorphisms. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
2 Second, using gene co-expression network analysis in control human subjects (N = 214; two frontal cortex regions) and expression quantitative trait loci mapping (N = 170 subjects), we show that expression of SST and the GABA-synthesizing enzymes glutamate decarboxylase 67 (GAD67) and GAD65 are tightly co-regulated and influenced by X-chromosome genetic polymorphisms. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens