Title : Expression and regulation of endothelin precursor mRNA in avascular human amnion.

Pub. Date : 1990 Jan 2

PMID : 2406172






1 Functional Relationships(s)
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1 Using the amnion cells in primary monolayer culture to investigate the regulation of preproendothelin mRNA expression, we found that epidermal growth factor (EGF) and interleukin-1 (IL-1) act to stimulate preproendothelin mRNA levels; in addition, the induction of preproendothelin mRNA by either of these agents is enhanced upon simultaneous treatment with cycloheximide. Cycloheximide interleukin 1 alpha Homo sapiens