Pub. Date : 2014 Mar
PMID : 24059317
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Hydrophobic interactions and hydrogen bonds both play an equally important role in the correct positioning of Cisplatin within the "acyl pocket" as well as "catalytic site" of AChE to permit docking. | Hydrogen | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
2 | During "Cisplatin-CAS site of AChE enzyme" interaction, it was found that out of the three amino acids constituting the catalytic triad (S203, H447 and E334), two amino acid residues namely S203 and H447 interact with Cisplatin by hydrogen bonding and hydrophobic interaction, respectively. | Hydrogen | acetylcholinesterase (Cartwright blood group) | Homo sapiens |