Title : Extensive post-translational modification of active and inactivated forms of endogenous p53.

Pub. Date : 2014 Jan

PMID : 24056736






2 Functional Relationships(s)
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1 We exploited this system to examine select post-translational modifications (PTMs) present on a transcriptionally inert population of endogenous human p53, as well as on p53 activated in response to etoposide treatment of normal human fibroblasts. Etoposide tumor protein p53 Homo sapiens
2 Despite the differences in activity, including greater in vitro sequence-specific DNA binding activity exhibited by p53 isolated from etoposide-treated cells, few differences were observed in the location, nature, or relative frequencies of PTMs on the two populations of human p53. Etoposide tumor protein p53 Homo sapiens