Pub. Date : 2013 Oct 15
PMID : 24048902
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | How NLRP3 senses these various stimuli is still poorly understood, but mitochondria and mitochondrial reactive oxygen species have been proposed to play a critical role in NLRP3 activation. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 2 | How NLRP3 senses these various stimuli is still poorly understood, but mitochondria and mitochondrial reactive oxygen species have been proposed to play a critical role in NLRP3 activation. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |
| 3 | Taken together, our results suggest that MAVS facilitates the recruitment of NLRP3 to the mitochondria and may enhance its oligomerization and activation by bringing it in close proximity to mitochondrial reactive oxygen species. | Reactive Oxygen Species | NLR family pyrin domain containing 3 | Homo sapiens |