Title : Isolation of a novel thioflavin S-derived compound that inhibits BAG-1-mediated protein interactions and targets BRAF inhibitor-resistant cell lines.

Pub. Date : 2013 Nov

PMID : 24048738






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In human breast cancer cell lines, with high BAG-1 expression levels, Thioflavin S reduces the binding of BAG-1 to Hsc70, Hsp70, or CRAF and decreases proliferation and viability. thioflavin T heat shock protein family A (Hsp70) member 4 Homo sapiens