Pub. Date : 2013 Dec
PMID : 24047423
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Landreth"s group in three murine models of AD has shown that the RXR agonist bexarotene (Targretin), Food and Drug Administration (FDA) approved and used since 1999 for the treatment of cutaneous T cell lymphoma, promotes a fast ApoE-dependent clearance of soluble Abeta peptides from the brain, reduces Abeta plaques, and stimulates the reversal of cognitive, social, and olfactory deficits. | Bexarotene | apolipoprotein E | Mus musculus |
| 2 | Landreth"s group in three murine models of AD has shown that the RXR agonist bexarotene (Targretin), Food and Drug Administration (FDA) approved and used since 1999 for the treatment of cutaneous T cell lymphoma, promotes a fast ApoE-dependent clearance of soluble Abeta peptides from the brain, reduces Abeta plaques, and stimulates the reversal of cognitive, social, and olfactory deficits. | Bexarotene | apolipoprotein E | Mus musculus |