Title : Transmembrane domain II of the human bile acid transporter SLC10A2 coordinates sodium translocation.

Pub. Date : 2013 Nov 8

PMID : 24045943






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Combined, our data propose that a consortium of sodium-sensitive residues along with previously reported residues (Thr(134), Leu(138), and Thr(149)) from TM3 may form the sodium binding and translocation pathway. Leucine tropomyosin 3 Homo sapiens
2 Notably, residues Gln(75), Met(79), Thr(82), and Leu(86) from TM2 are highly conserved in TM3 of a putative remote bacterial homologue (ASBTNM), suggesting a universal mechanism for the SLC10A transporter family. Leucine tropomyosin 3 Homo sapiens