Title : Two ABCB4 point mutations of strategic NBD-motifs do not prevent protein targeting to the plasma membrane but promote MDR3 dysfunction.

Pub. Date : 2014 May

PMID : 24045840






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The ABCB4 gene encodes for MDR3, a protein that translocates phosphatidylcholine from the inner to the outer leaflet of the hepatocanalicular membrane; its deficiency favors the formation of "toxic bile". Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens
2 The ABCB4 gene encodes for MDR3, a protein that translocates phosphatidylcholine from the inner to the outer leaflet of the hepatocanalicular membrane; its deficiency favors the formation of "toxic bile". Phosphatidylcholines ATP binding cassette subfamily B member 4 Homo sapiens