Pub. Date : 2014 Apr
PMID : 24045439
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Similarly, sunitinib, a small-molecule inhibitor of RET, blocked GDNF-mediated activation of ERK and AKT. | Sunitinib | ret proto-oncogene | Homo sapiens |
2 | Inhibition of RET either by gene knockdown or by treatment with sunitinib or vandetanib reduced RET-dependent growth of luminal breast cancer cells. | Sunitinib | ret proto-oncogene | Homo sapiens |
3 | Inhibition of RET either by gene knockdown or by treatment with sunitinib or vandetanib reduced RET-dependent growth of luminal breast cancer cells. | Sunitinib | ret proto-oncogene | Homo sapiens |
4 | Parallel experiments using treatment with tamoxifen and sunitinib confirmed the increased effectiveness of dual inhibition of the ER and RET pathways in regulating cell growth. | Sunitinib | ret proto-oncogene | Homo sapiens |