Title : Synergistic apoptosis of CML cells by buthionine sulfoximine and hydroxychavicol correlates with activation of AIF and GSH-ROS-JNK-ERK-iNOS pathway.

Pub. Date : 2013

PMID : 24040019






3 Functional Relationships(s)
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1 Synergistic apoptosis of CML cells by buthionine sulfoximine and hydroxychavicol correlates with activation of AIF and GSH-ROS-JNK-ERK-iNOS pathway. Reactive Oxygen Species nitric oxide synthase 2 Homo sapiens
2 Activation of ROS- dependent JNK played a crucial role in ERK1/2 activation which subsequently induced the expression of inducible nitric oxide synthase (iNOS). Reactive Oxygen Species nitric oxide synthase 2 Homo sapiens
3 Activation of ROS- dependent JNK played a crucial role in ERK1/2 activation which subsequently induced the expression of inducible nitric oxide synthase (iNOS). Reactive Oxygen Species nitric oxide synthase 2 Homo sapiens